Active Cutaneous Anaphylaxisの検討
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Using egg-albumin as an antigen, experimental condition of active cutaneous anaphylaxis (ACA) reaction in guinea pig was studied comparing with that of Arthus reaction and systemic anaphylactic shock. 1) The blueing area was measured at different time after antigen challenge and dye injection. The most appropriate measurement was obtained 60 min after dye injection which followed the antigen challenge immediately. 2) Time response of intensities of hemorrage caused by Arthus reaction and of blueing by ACA-reaction was studied. It was observed that ACA-reaction is temporary and the weak reaction at delayed time is followed by increasing intensity of Arthus reaction. 3) Comparing susceptibilities between ACA-reaction, systemic anaphylactic shock and Schultz-Dale reaction, highest susceptibility and smallest antigen dose in ACA-reaction was observed. 4) The same inclination was observed in ACA-reaction and systemic anaphylactic shock by comparative study of influence at challenge days after sensitization.
- 1967-12-30
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