肝臓アレルギーに関する研究 : 第1編 感作と臓器細胞の反応性についての検討

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概要

• 論文の詳細を見る

• Process of sensitization in rabbits with some organ antigens and effect of organ antibody upon the reactivility of the corresponding organ-cells were studied and obtained the following results: 1. The anamnestic reaction in animal sensitized with liver extracted antigen was induced by the same reaction as it sensitized with heterogeneous proteins or bacillus. 2. The anamnestic reaction in animals sensitzed with homologous or heterogeneous liver antigens was induced remarkably by corresponding antigens rather than adrenocortical extract. 3. In the living organ sensitized with homologous or heterogeneous liver extract, reactions of the reticuloendotherial systems were almost the same with those sensitized with heterogeneous proteins. 4. In the electron-microscopic findings of the liver cells sensitized with liver extract, change of endoplasmic reticulum was almost invariably observed, as was seen in the liver cells sensitized with heterogeneous protein. 5. The electrophoretic mobility of the liver cells sensitized with liver extract or heterogenous proteins increased remarkably in the Tyrode solution to which the correspondent antiserum was added beforehand. 6. Phase contrast microscopic findings of the liver cells sensitized with liver antibody were changed according to the increasing electrophoretic mobility. By these facts, the changes of reactivility in the liver cells on the sensitizing process with the liver extract or heterogenous proteins were proved.

• 日本アレルギー学会の論文
• 1961-07-30

著者

• 田辺 功

  朝日新聞東京本社科学部編集委員

• 田辺 功

  岡山大学第1内科学教室

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