結核死菌静脈内注射による肺内病巣形成におよぼす肺内注入抗体の影響

概要

論文の詳細を見る
l. Serum from the rabbit sensitized with heat-killed tuberculous bacilli, showing highly elevated antibody titers, was injected into the right posterior lobe of the lung of guinea pigs and 4 hours later the antigen bacilli were intravenously injected in the same animals. 2. A large granuloma was formed in the injected lung lobe, 48 hours after the intravenous injection of antigen. 3. A similar lesion never took place in the control aterial lung into which normal rabbit serum had been injected as the control. 4. Accordingly, it seems likely that humoral antibodies against tuberculous bacilli have an important role on the formation of granulomatous lesions in the lung.
日本アレルギー学会の論文
1969-02-28