5 難治性根尖性歯周炎病巣から分離されたバイオフィルムを形成する通性嫌気性グラム陰性桿菌の性状(第500回大阪歯科学会例会)

概要

論文の詳細を見る
I identified viscous-material-producing facultative anaerobic Gram-negative rods that were isolated from a therapy-resistant apical periodontitis lesion as Escherichia hermannii strains. I named them E. hermannii strains 11-1 to 6. These bacteria were surrounded by mesh-like structures which are typical of biofilm-forming bacteria. The culture medium of strain 11-2 had the highest viscosity of the six strains. When I purified exopolysaccharide (EPS) from this culture medium and analyzed its chemical composition, I found it consisted primarily of polysaccharide that contained 80% mannose. Susceptibilities of these strains to anti-microbial agents did not show any particular pattern. My data suggests that E. hermannii, a transient bacterium in the oral cavity, might form biofilm in the periapical region and cause therapy-resistant apical periodontitis.
大阪歯科学会の論文
2005-12-25