Lethal Effect of Thermal Neutrons on Hypoxic Elirlich Ascites Tumour Cells in vitro

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概要

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• Ehrlich ascites tumour cells were irradiated in vitro with thermal neutrons under aerobic and hypoxic conditions, and the survival of their reproductive capacity was assayed in vivo. Only a slight hypoxic protection was observed for thermal neutron irradiation with an oxygen enhancement ratio (OER) of 1.2, as compared with OER of 3.3 for ^<60>Co-γ-rays. Absorbed dose of thermal neutrons was calculated by assuming that the energies of recoiled nuclei were completely absorbed within a cell nucleus. This led to a conclusion that the RBE of thermal neutrons were 1.3 and 3.6 for the oxygenated and the hypoxic cell fractions, respectively.

• 日本放射線影響学会の論文

著者

• AKABOSHI Mitsuhiko

  Reseasrch Reactor Institute, Kyoto University

• KAWAI Kenichi

  Research Reactor Institute, Kyoto University

• Kawai Kumi

  Department Of Pathology Aichi Medical University School Of Medicine

• Kawai K

  Nagoya Univ. School Of Medicine Nagoya

• Kawai Kenichi

  Research Reactor Institute Kyoto University

• Akaboshi Mitsuhiko

  Research Reactor Institute Kyoto University

• Maki H

  Research Reactor Institute Kyoto University

• Kawai K

  Research Reactor Institute Kyoto University

• Akaboshi M

  Kyoto Univ. Ohsaka Jpn

• MAKI HIROTOSHI

  Research Reactor Institute, Kyoto University

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