Effects of X-radiation on the Metabolism of Nucleic Acids in Rat Spleen Cells during the Course of Primary Immune Response

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概要

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• 1. Male Wistar rats were immunized with BGG and the effects of X-radiation on the nucleic acids in their spleen were studied during the period of primary immune response. 2. Amount of DNA increased on the 9th day of immune response reaching twice as much as the unimmunized rats. DNA was markedly reduced by the irradiation with 500 r of X-ray. 3. RNA increased also on the 10th day and it was reduced considerably by X-ray. 4. Particular changes caused by the administration of antigen were found in the chromatographic pattern of RNA by DEAE-cellulose columm, and X-ray diminished such changes ascribed to an immune response.

• 日本放射線影響学会の論文

著者

• 森 和博

  Laboratory Of Radiation Biology Faculty Of Science: (present Address) Department Of Anatomy Okayama

関連論文

• Effects of X-radiation on the Metabolism of Nucleic Acids in Rat Spleen Cells during the Course of Primary Immune Response

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