Evaluation of Functional Reversibility of Ischemic Brain-To select appropriate patients with completed stroke for STA-MCA bypass surgery
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概要
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The purpose of this paper is to present a new method by which the functional reversibility of the ischemic brain can be evaluated by changes of somatosensory evoked potentials (SEP) in induced-hypertension. The method (called functional SEP test) was useful in selecting appropriate candidates of completed stroke for superficial temporal artery (STA) -middle cerebral artery (MCA) anastomosis. To evaluate the grade of reversible hypofunction of ischemic brain, cerebral blood flow (CBF) dynamics and SEPs during induced-hypertension were measured before, during and after operation in 19 completed stroke patients with main trunk occlusion of MCA. As control studies, cerebral angiographies and CBF studies were performed in 29 conservatively treated cases. Furthermore, preoperative angiographical findings, STA-MCA shunt flow and blood pressure of STA and MCA were examined respectively in surgically treated cases. From these studies, our present criteria for bypass operation evolved as follows: l) Mean CBF value is in 25 to 32 ml/100g/min without global loss of autoregulation and CO_2 -reactivity; 2) Amplitude of initial component of SEP is augmented 2 times or more during induced-hypertension than at rest state; 3) The N_1 -amplitude ratio of the normal side to the affected side is above 0.5 at rest state and increased approximately to normal value, i.e., 1.0 by induced-hypertension; and 4) The STA-MCA shunt flow through STA is in 40 to 90 ml/min and the MCA blood pressure is in 40 to 60 mmHg.
- 社団法人日本脳神経外科学会の論文
著者
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Uemura Kazuo
Divisions Of Radiology Research Institute Of Brain And Blood Vessels
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Uemura Kazuo
Division Of Radiology Research Institute Of Brain And Blood Vessels
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Uemura Kazuo
Division Of Surgical Neurology And Radiology
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Suzuki Akifumi
Research Institute Of Brain And Blood Vessels
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ITO Zentaro
Research Institute of Brain and Blood Vessels
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HEN Rhyshu
Research Institute of Brain and Blood Vessels
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NAKAJIMA Kenji
Research Institute of Brain and Blood Vessels
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MORIYAMA Takashi
Research Institute of Brain and Blood Vessels
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