MECHANISM OF RETARDED MENTAL DEVELOPMENT IN MSP-INDUCED SFD RATS, ESPECIALLY ON DNA SYNTHETIC RATE OF THE BRAIN
スポンサーリンク
概要
- 論文の詳細を見る
Development of mental or behavioral activity after birth of small for date (SFD) rats produced by injection of microspheres at the 18th day of gestation was studied, and obtained the following results: 1. Brain weight of the SFD group increased at a lower level than the control group, but there was significant difference in the brain/body weight ratio between SFD and the control; the SFD group retained a higher value than the control. 2. The peak of brain DNA synthetic rate which measured by intraperitoneal (i.p.) injection of H^3-thymidine was shown at the 10th day after birth in the control group, but it was delayed four days in the SFD group. 3. The maximum incorporation of H^3-thymidine into brain cells was studied by autoradiography. The rate was corresponded to the peak of brain DNA synthetic rate. 4. Content of cytochrome c in the brain mitochondria also increased in higher level than the control group, but there was no difference in the content of cytochrome a between both SFD and the control group. From these results we discussed the biochemical basis of the process of mental development of SFD after birth.
- 社団法人日本産科婦人科学会の論文
- 1978-01-01
著者
-
YAMAGUCHI Ryuji
Department of Occupational Therapy, School of Health Science, Kibi International University
-
Noda Tsuneo
Department of Obstetrics and Gynecology, Higashi-Osaka Central Hospital
-
Ueda Shuji
Department Of Hematology/oncology Osaka University Graduate School Of Medicine
-
Noda Tsuneo
Department Of Obstetrics And Gynecology Nara Medical University
-
Noda Tsuneo
Department Of Obstetrics And Gynecology Higashi-osaka Central Hospital
-
Yamaguchi Ryuji
Department Of Neuropharmacology Faculty Of Pharmaceutical Sciences Fukuoka University
-
森山 郁子
Department of Obstetrics and Gynecology, Nara Medical University
-
UEDA Shuji
Department of Agriculture, Forestry and Fisheries, Fukuoka Prefectural Government, Fukuoka 812-8577, Japan
-
YAMAGUCHI Ryuji
Department of Obstetrics and Gynecology, Nara Medical University
関連論文
- ESTABLISHMENT OF NEUROTRANSMITTER-HYPERSENSITIVE PC12 VARIANT CELLS DEFICIENT IN NERVE GROWTH FACTOR-INDUCED NEURITE OUTGROWTH
- Ovarian neuroblastoma due to malignant transformation of mature cystic teratoma : A clinicopathologic and immunohistologic analysis
- STUDIES ON THE PERINATAL LIVER FUNCTIONS OF EXPERIMENTAL SMALL FOR DATE (SFD) RAT
- Reducing Acyl Migration during Purification of 2-Arachidonoylglycerol from Biological Samples before Gas Chromatography Mass Spectrometry Analysis
- Cooling Properties of Neutron Stars with Quark Matter
- Constitutively Activated Rho Gunosine Triphosphatases Regulate the Growth and Morphology of Hairy Cell Leukemia Cells
- Constitutive Activation of c-kit by the Juxtamembrane but Not the Catalytic Domain Mutations Is Inhibited Selectively by Tyrosine Kinase Inhibitors STI571 and AG1296
- KIT MUTATIONS IN HEMATOPOIETIC MALIGNANCIES
- EFFECTS OF ENALAPRIL ON LEFT VENTRICULAR FUNCTION AND MASS IN PATIENTS WITH ESSENTIAL HYPERTENTION
- Statin Therapy Can Prevent In-Stent Restenosis (ISR) after Coronary Stenting in the Patient with Acute Coronary Syndrome (ACS)
- STUDIES ON THE SOMATIC AND MENTAL DEVELOPMENT IN EXPERIMENTALLY INDUCED SFD RAT AFTER BIRTH
- MECHANISM OF RETARDED MENTAL DEVELOPMENT IN MSP-INDUCED SFD RATS, ESPECIALLY ON DNA SYNTHETIC RATE OF THE BRAIN
- Clinical evaluation of a new bleaching product "Polanight" in a Japanese population
- Effects of a New Triple-α Reaction on X-Ray Bursts of a Helium-Accreting Neutron Star
- Renal biopsy is a helpful tool for the diagnosis of POEMS syndrome
- Development of a Single Bovine Embryo Improved by Co-culture with Trophoblastic Vesicles in Vitamin-supplemented Medium
- Effects of a New Triple-α Reaction on X-Ray Bursts of a Helium-Accreting Neutron Star
- Stringent Complete Remission of Primary Plasma Cell Leukemia with Reduced-dose Bortezomib, Lenalidomide and Dexamethasone: A Case Report and Review of the Literature