TERATOLOGICAL STUDY OF HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE IN RABBITS
スポンサーリンク
概要
- 論文の詳細を見る
A teratogical study was carried out in New Zealand White rabbits in order to examine the teratogenic potentiality of HPMCAS, a useful pharmaceutical excipient. HPMCAS was orally administered at dose levels of 625, 1,250 and 2,500 mg/kg/day for a period of 13 days from day 6 to day 18 of gestation. All pregnant females were sacrificed on day 29 of gestation and their fetuses were examined. The administration of HPMCAS during a period of organogenesis produced no embryotoxic and teratogenic effects as well as no influence on behavior, appearance and growth of animals.
- 日本トキシコロジー学会の論文
- 1985-10-31
著者
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Ueno Koichi
Laboratory Of Biochemical Pharmacology And Biotoxicology Faculty Of Pharmaceutical Sciences Chiba Un
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Igarashi Takashi
Laboratory Of Biochemical Pharmacology And Biotoxicology Faculty Of Pharmaceutical Sciences Chiba Un
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KITAGAWA HARUO
Laboratory of Biochemical Pharmacology and Biotoxicology, Faculty of Pharmaceutical Sciences, Chiba
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Ueno K
Laboratory Of Biochemical Pharmacology And Biotoxicology Faculty Of Pharmaceutical Sciences Chiba Un
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Ueno Koichi
Department Of Geriatric Pharmacology And Therapeutics Graduate School Of Pharmaceutical Sciences Chi
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Igarashi Takashi
Department Of Pediatrics Branch Hospital Faculty Of Medicine University Of Tokyo
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Ueno Koichi
Laboratory Of Biochemical Pharmacology And Biotoxicology Department Of Drug Evaluation And Toxicolog
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HOSHI Noboru
Laboratory of Biochemical Pharmacology and Biotoxicology, Department of Drug Evaluatign and Toxicolo
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Hoshi Noboru
Laboratory Of Biochemical Pharmacology And Biotoxicology Department Of Drug Evaluatign And Toxicolog
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Kondo Yuko
Nippon Bio-test Laboratories Inc.
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Kitagawa Haruo
Laboratory Of Hospital Pharmacy Faculty Of Pharmaceutical Sciences Chiba University:division Of Anal
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Kitagawa Haruo
Laboratory Of Biochemical Pharmacology And Blotoxicology Faculty Of Pharmaceutical Sciences Chiba Un
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Kitagawa Haruo
Laboratory Of Biochemical Pharmacology And Biotoxicology Department Of Drug Evaluation And Toxicolog
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Igarashi T
Eisai Co. Ltd. Ibaraki Jpn
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FUJITA Teruko
Nippon Bio-Test Laboratories Inc.
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ICHIKAWA Nobuo
Nippon Bio-Test Laboratories Inc.
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ISODA Masae
Department of Pathology, Nippon Veterinary and Zootechnical College
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Isoda Masae
Department Of Pathology Nippon Veterinary And Zootechnical College
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ICHIKAWA Naoto
Bio-Medical Research Laboratories Co., Ltd.
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Ichikawa Naoto
Bio-medical Research Laboratories Co. Ltd.
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Kitagawa Haruo
Laboratory Of Biochemical Pharmacology And Toxicology Faculty Of Pharmaceutical Sciences Chiba Unive
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Kitagawa Haruo
Analytical And Metabolic Research Laboratories And Biological Research Laboratories Sankyo Co. Ltd.:
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Ueno Koichi
Dep. Of Geriatric Pharmacology Graduate School Of Pharmaceutical Sciences Chiba Univ.
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Kitagawa H
Laboratory Of Hospital Pharmacy Faculty Of Pharmaceutical Sciences Chiba University:division Of Anal
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Igarashi Takashi
千葉大学 薬
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Igarashi Takashi
Analytical And Metabolic Research Laboratories And Biological Research Laboratories Sankyo Co. Ltd.:faculty Of Pharmaceutical Sciences Chiba University
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KITAGAWA Haruo
Laboratory of Biochemical Pharmacology and Biotoxicology
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UENO Koichi
Laboratory of Biochemical Pharmacology and Biotoxicology
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