2種の硝酸イソソルビド徐放性製剤からの薬物放出挙動

概要

論文の詳細を見る
As an evaluation of sustained release preparations, release patterns of two sustained release preparations of isosorbide dinitrate were examined. Comparisons were made between Nitrol R and Frandol in respect to the effects of stirring methods, rates of stirring and a surfactant on the release patterns of the drug. Dependence of release patterns on stirring methods and rates of stirring was less in Nitrol R than that in Frandol. In both preparations ,release rates were higher in a release medium with surfactant and more variable than those without surfactant.
日本医療薬学会の論文
1984-06-20