Relationship between Initial Blood Flow Changes and Histological Changes in Periodontal Tissue during Tooth Movement
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概要
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The purpose of the present study was to investigate the relationship between initial blood flow changes and histological changes on the pressure side of periodontal tissue during tooth movement in rats. Ninety-seven male Wistar rats weighing 220-250g were used. Rubber bands of three different thicknesses (0.65mm×1.0mm×1.0mm, 1.0mm×1.0mm×1.0mm, and 1.5mm×1.0mm×1.0mm) were inserted into the interproximal space between the maxillary first and second molars using the method of Waldo. Gingival blood flow measurements were done with a laser doppler flowmeter, periodontal blood flow measurements were carried out using the hydrogen clearance method, and histological examinations were performed by the quantitative method using photomicrographs. Osteoclasts were stained by the acid phosphatase and tartrate-resistant acid phosphatase methods. Larger forces induced increasingly larger reductions in blood flow in the pressure area of periodontal tissue. More time was required in the periodontium than in the gingivae to get from maximum blood flow reduction to the base line. Larger forces on the tooth created hyalinized tissue earlier and created a wider hyalinized area. Larger forces introduced many osteoclasts and were transmitted to a wider area of periodontal tissue, creating conditions for future dramatic reorganization of this tissue. Forces beyond this level may create severe damage. Even if the force is not large, severe root resorption may occur due to a concentration of forces in the area. Many osteoclasts appeared in the vicinity of vessels. They seemed to concentrate in areas where tissue blood volume had increased. Osteoclastic activities might be closely related to blood during experimental tooth movement. Knowledge of blood flow measurements contributes to the proper determination of treatment methods, appliances and optimum forces in clinical orthodontic treatment.
- 大阪歯科学会の論文
著者
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Inubushi Toshitsugu
Osaka Dental Univ. Osaka Jpn
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INUBUSHI Toshitsugu
Graduate school of Dentistry, Osaka Dental University