二次性能動輸送機構の統一的モデル

概要

論文の詳細を見る
Na^+ / glutamate, Na^+ / proline and H^+ / lactose transport systems in Escherichia coli are typical secondary active transport systems. On the basis of the properties of substrate binding to carriers, the ordered binding model for the mechanistic mechanism of the energy coupling was proposed, which was shown to explain well the transport properties of these secondary active transport systems. The specific properties of these transport systems were also summarized and shown to be explained by assuming special conditions within the framework of this general ordered binding model. Since many possible mechanisms for secondary active transport systems seem in general to be ruled out by the ordered binding mechanism, this mechanism probably has some biological significance. Thus, I propose that, for the same reason, other possible energy transducing machineries could also be ruled by this ordered binding mechanism.
日本生物物理学会の論文
1992-07-25