<原著>クエン酸刺激によるヒト混合唾液の最大分泌量について

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It is well known that in humans the volume of saliva induced reflexly by taste stimulation varies markedly, depending on the nature of the stimulus. Of the four basik taste stimuli (acid, salt, sweet and bitter) , acid is by far the most potent even when the subjective intensities of the four stimuli are equal. Most of the previous studies of salivary secretion in man in response to acid solution have been done with parotid saliva. The purpose of the present study was to determine the optimum concentration of acid necessary to elicit maximal whole salivary flow rate. The subjects were 32 young adults, 16 females and 16 males, and the studies were carried out at about 12:00 noon. 1% citric acid was infused into the mouth through a plastic tube, at a rate of exactly 5.0 ml/min, by means of a peristaltic pump. The subjects spat out the acid and any saliva into a weighed container about every 10 second. The volume accumulated in the 1 min, minus the 5.0 ml of infused acid, was regarded as stimulated flow rate of saliva. After a rest period of a few minutes, this was repeated with 3% and then 5% citric acid. The salivary flow rates were expressed both as ml/min and as a percentage of that in response to 5% citric acid since, in all 32 subjects, the 5% citric acid elicited the highest flow rate (7.08 ± 2.16 ml/min) . There were no difference in flow rate due to gender and the mean flow rate elicited 1% and 3% citric acid were 4.35 ±1.92 ml/min, 60.1 ± 17.7% and 5.94 ± 2.08 ml/min, 83.0 ± 11.7%, respectively. There was a significant correlation between the unstimulated flow rate and the stimulated flow rate in response to the all concentrations of citric acid.
北海道医療大学の論文
1988-06-30

<原著>クエン酸刺激によるヒト混合唾液の最大分泌量について

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