<原著>死体腎移植における予後因子の検討

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Various factors affecting prognosis and graft survival were investigated in 50 patients who underwent cadaveric renal transplantation in our institution. The 5-year graft survival rate was significantly (p<0.05) higher in the cyclosporine treated group than in the group treated with conventional therapy, but there was no significant difference between the two groups in 5-year patient survival rate. There was no correiation between warm ischemic time and duration of acute tubular necrosis. There was no correlation between total ischemic time and duration of acute tubular necrosis. There was no significant difference between patients in whom duration of acute tubular necrosis was over 10 days and those in whom it was 10 days or less in 5-year graft survival rate, but 5-year graft survival rate was higher in the latter. The 5-year graft survival rate was significantly higher in patients with warm ischemic time of 5 minutes or less than in those in whow it was over 5 minutes. There was no significant difference between patients with total ischemic time of over 6 hours and those in whom it was 6 hours or less in 5-year graft survival rate. To reduce acute tubular necrosis, 5 patients were administered lipo-prostaglaindn E_1,but this treatment was not found to be effective in reducing acute tubular necrosis. We conclude that warm ischemic time and duration of acute tubular necrosis are the most important factors affecting prognosis of cadaveric recal transplant patients.
1992-09-25

<原著>死体腎移植における予後因子の検討

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