Pathogenesis of Tuberculous Meningitis

概要

論文の詳細を見る
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。The observations on the spread specimens of 10 cases of tuberculous meningitis and 1 case of miliary tuberculosis revealed that the lesion of the meninges consisted of miliary tubercles and diffuse perivascular exudation. The former is caused by hematogenous installation of tubercle bacilli, while the latter is due to the bacillary dissemination in the cerebrospinal fluid. These were proved by the two kinds of experiments of the injection of tubercle bacilli both intravenously and intrathecally. Tuberculous meningitis is pathogenetically regarded as dissemination in the meninges caused by the bacilli discharged into subarachnoid space from the miliary tubercle, and the typical clinical symptoms of tuberculous meningits is characterized by its collateral inflammation or diffuse perivascular exudation. The author wishes to extend grateful acknowledgments to Prof. H. Nagai and Prof. I. Sagawa for the sincere advice and encouragement for this work. This study has been reported at the 56th Japanese Pediatric Congress 1953,and the 30th Japanese Tuberculosis Congress 1956. This study was aided in part by a grant from the Fundamental Scientific Research provided by the Ministry of Education.
京都大学の論文
1956-06-25