<Originals>Improvement of wall motion abnormality after percutaneous transluminal coronary angioplasty in patients with healed myocardial infarction
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概要
- 論文の詳細を見る
Regional wall motion abnormality in the infarcted myocardium sometimes improves after successful percutaneous transluminal coronary angioplasty (PTCA) of the infarct-related coronary artery. The purpose of the present study was to find out clinical indices which predict the improvement of the wall motion abnormality after successful PTCA in patients with healed myocardial infarction (MI). In 71 patients with MI who underwent successful PTCA, global and regional ejection fractions (EF) were analyzed by the left ventriculography before and 4 months after PTCA. Both global and regional EFs were not improved in 29 patients with restenosis after PTCA, but those were improved in 42 patients without restenosis from 58+9 to 61+8% for global EF (p<0.005) and from 39±16 to 45±15% for regional EF (p<0.005) by PTCA. In 18 patients with angina pectoris after MI among those 42 patients, global EF was improved from 58±11 to 63±7% by PTCA (p<0.05). In 12 patients who showed increased ECG-R wave in infarct site among those 42 patients, global EF was improved from 60±7 to 67±4% by PTCA (p<0.001). In either of the groups of patients who had no coronary thrombolysis in acute phase, coronary stenosis of TIMI grade 3 before PTCA, anterior MI, peak creatine kinase level greater than 1,000IU/l and global EF less than 60% before PTCA, both global and regional EFs were improved after successful PTCA. Conclusions. Angina after MI and increased ECG-R wave, provided the absence of PTCA, indicate the presence of hibernating myocardium in the infarct site and the wall motion abnormality in this site can be improved by PTCA.
- 近畿大学の論文
著者
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KOKA HIRONARI
First Department of Internal Medicine, Kinki University School of Medicine
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Koka Hironari
First Department Of Internal Medicine Kinki University School Of Medicine
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