BMI is Strongly Associated With Hypertension, and Waist Circumference is Strongly Associated With Type 2 Diabetes and Dyslipidemia, in Northern Chinese Adults
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概要
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Background: Obesity is closely associated with chronic diseases such as hypertension, type 2 diabetes mellitus (T2DM), and dyslipidemia. We analyzed the optimal obesity index cut-off values for metabolic syndrome (MetS), and identified the obesity index that is more closely associated with these chronic diseases, in a population of northern Chinese.<BR>Methods: We surveyed 8940 adults (age, 20–74 years) living in northern China for chronic diseases. Receiver operating characteristics (ROC) analysis, relative risk, and multivariate regression were used to develop an appropriate index and optimal cut-off values for MetS and obesity-related chronic diseases.<BR>Results: Waist circumference (WC) and body mass index (BMI) were good markers for MetS, WC was a good marker for T2DM and dyslipidemia, and BMI was a good marker for hypertension. The optimal BMI cut-off value of MetS was 24 kg/m2, and the optimal WC cut-offs were 86 cm and 78 cm in men and women, respectively. Relative risk regression models showed that BMI was associated with hypertension, T2DM, and hypertriglyceridemia and a higher prevalence ratio (PR) for hypertension: 2.35 (95% CI, 2.18–2.50). WC was associated with T2DM, hypertension, and hypertriglyceridemia, with PRs of 2.05 (1.63–2.55) for T2DM and 2.47 (2.04–2.85) for hypertriglyceridemia. In multivariate regression models, the standardized regression coefficients (SRCs) of BMI were greater for SBP and DBP, and the SRC of WC was greater for fasting blood glucose, 2-hour postload blood glucose, triglyceride, and total cholesterol.<BR>Conclusions: Our analysis of a population of northern Chinese indicates that the optimal cut-off values for MetS are WCs of 86 cm in men and 78 cm in women and a BMI of 24 kg/m2 in both sexes. BMI was strongly associated with hypertension, while WC was strongly associated with T2DM and dyslipidemia.
- 2012-07-01
著者
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Li Kang
Department Of Cardiology Beijing Hospital
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Zhao Chen
Department Of Pathology College Of Basic Medical Sciences China Medical University
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Wang Cheng
Department Of Nutrition And Food Hygiene Public Health College Harbin Medical University
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Feng Rennan
Department Of Nutrition And Food Hygiene Public Health College Harbin Medical University
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Sun Changhao
Department Of Nutrition And Food Hygiene Public Health College Harbin Medical University
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Li Kang
Department Of Nutrition And Food Hygiene Public Health College Harbin Medical University
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Li Ying
Department Of Nutrition And Food Hygiene Public Health College Harbin Medical University
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Li Ying
Department Of Biochemistry And Molecular Biology Nihon University School Of Dentistry At Matsudo
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Li Song-tao
Department Of Nutrition And Food Hygiene School Of Public Health Harbin Medical University
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FENG Ren-Nan
Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University
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WANG Cheng
Endemic Disease Control Center, Chinese Center for Disease Control and Prevention, Harbin Medical University
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NIU Yu-Cun
Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University
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GUO Fu-Chuan
Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University
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SUN Chang-Hao
Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University
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Niu Yu-cun
Department Of Nutrition And Food Hygiene School Of Public Health Harbin Medical University
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Guo Fu-chuan
Department Of Nutrition And Food Hygiene School Of Public Health Harbin Medical University
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Zhao Chen
Department Of Nutrition And Food Hygiene School Of Public Health Harbin Medical University
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Wang Cheng
Endemic Disease Control Center Chinese Center For Disease Control And Prevention Harbin Medical University
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Li Kang
Department Of Biostatistics School Of Public Health Harbin Medical University
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