Breakthrough lung Scedosporium prolificans infection with multiple cavity lesions in a patient receiving voriconazole for probable invasive aspergillosis associated with monoclonal gammopathy of undetermined significance (MGUS)

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概要

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• Breakthrough non- Aspergillus mold infections among patients receiving the anti-mold azole antifungal agents like voriconazole or posaconazole have been increasingly reported. We report a case of lung Scedosporium prolificans infection with multiple cavities in a 58-year-old man with monoclonal gammopathy of undetermined significance (MGUS) during voriconazole treatment for probable invasive aspergillosis. Cultures of repeated sputum specimens yielded the same fungus until his death 83 days after diagnosis. S. prolificans should be considered in patients with breakthrough infections receiving voriconazole.

• 日本医真菌学会の論文
• 2011-01-31

著者

• Seyama Kuniaki

  Department Of Respiratory Medicine

• Tsuchiya Koji

  Department Of Cardiovascular Surgery Yamanashi Central Hospital

• YOSHIMI Kaku

  Department of Respiratory Medicine

• Misawa Shigeki

  Department Of Biotechnology Graduate School Of Engineering Osaka University

• Nagaoka Tetsutaro

  Department Of Respiratory Medicine Juntendo University School Of Medicine

• Kikuchi Ken

  Department Of Infection Control Science Faculty Of Medicine Juntendo University

• Takahashi Kazuhisa

  Department Of Biochemistry And Biotechnology Faculty Of Agriculture And Life Science Hirosaki Univer

• Kato Motoyasu

  Department Of Dental Anesthesiology Faculty Of Dentistry Health Sciences University Of Hokkaido

• Misawa Shigeki

  Department Of Clinical Laboratory Juntendo University Hospital

• OHASHI Rina

  Department of Respiratory Medicine, Juntendo University

• KATSURA Yoko

  Department of Respiratory Medicine, Juntendo University

• TAKEKAWA Hidenori

  Department of Respiratory Medicine, Juntendo University

• HOSHIKA Yoshito

  Department of Respiratory Medicine, Juntendo University

• SUGAWARA Tomonori

  Department of Respiratory Medicine, Juntendo University

• TOGO Shinsaku

  Department of Respiratory Medicine, Juntendo University

• Ohashi Rina

  Department Of Respiratory Medicine Juntendo University

• Katsura Yoko

  Department Of Respiratory Medicine Juntendo University

• Togo Shinsaku

  Department Of Respiratory Medicine Juntendo University

• Hoshika Yoshito

  Department Of Respiratory Medicine Juntendo University

• Takekawa Hidenori

  Department Of Respiratory Medicine Juntendo University

• Sugawara Tomonori

  Department Of Respiratory Medicine Juntendo University

• Tsuchiya Koji

  Department Of Clinical Laboratory Juntendo University Hospital

• Takahashi Kazuhisa

  Department Of Respiratory Medicine Juntendo University

• Seyama Kuniaki

  Department Of Respiratory Medicine Juntendo University

• Yoshimi Kaku

  Department Of Respiratory Medicine Juntendo University

• Takahashi Kazuhisa

  Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo

• Nagaoka Tetsutaro

  Department Of Respiratory Medicine Juntendo University

• Kato Motoyasu

  Department Of Respiratory Medicine Juntendo University

• Tsuchiya Koji

  Department of Applied Chemistry, Faculty of Science, Tokyo University of Science

• MISAWA Shigeki

  Department of Clinical Laboratory, Juntendo University Hospital

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