A Computer-Aided Distinction Method of Borderline Grades of Oral Cancer
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概要
- 論文の詳細を見る
We have developed a new computer-aided diagnostic system for differentiating oral borderline malignancies in hematoxylin-eosin stained microscopic images. Epithelial dysplasia and carcinoma in-situ (CIS) of oral mucosa are two different borderline grades similar to each other, and it is difficult to distinguish between them. A new image processing and analysis method has been applied to a variety of histopathological features and shows the possibility for differentiating the oral cancer borderline grades automatically. The method is based on comparing the drop-shape similarity level in a particular manually selected pair of neighboring rete ridges. It was found that the considered similarity level in dysplasia was higher than those in epithelial CIS, of which pathological diagnoses were conventionally made by pathologists. The developed image processing method showed a good promise for the computer-aided pathological assessment of oral borderline malignancy differentiation in clinical practice.
- （社）電子情報通信学会の論文
- 2010-08-01
著者
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KIKUCHI Hisakazu
Department of Electrical and Electronic Engineering, Niigata University
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MURAMATSU Shogo
Department of Electrical and Electronic Engineering, Niigata University
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Saku Takashi
Divisions of Oral Pathology, Department of Tissue Regeneration and Reconstruction, Niigata Universit
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Sami Mustafa
Department Of Electrical And Electronic Engineering Graduate School Of Science And Technology
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Muramatsu S
Department Of Electrical And Electronic Engineering Niigata University
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Muramatsu Shogo
Niigata Univ. Niigata Jpn
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Saku Takashi
Division Of Oral Pathology Department Of Tissue Regeneration And Reconstruction Niigata University G
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Saku Takashi
Division Of Oral Pathology Graduate School Of Medical And Dental Sciences Niigata University
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Kikuchi Hisakazu
Niigata Univ. Niigata Jpn
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Kikuchi Hisakazu
Dept. Of Electrical And Electronic Eng. Niigata University
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Kikuchi Hisakazu
Department Of Electrical And Electronic Engineering Graduate School Of Science And Technology
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Muramatsu Shogo
Department Of Electrical And Electronic Engineering Niigata University
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Muramatsu Shogo
Dept. Of Electrical And Electronic Eng. Niigata University
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Saito Masahisa
Imaging Science And Engineering Laboratory Tokyo Institute Of Technology
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Saito Msahisa
Imaging Science and Engineering Laboratory, Tokyo Institute of Technology
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