Analysis of Standard and Irregular Patterns in a Simulated Human Magnetocardiogram

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概要

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• We present a study of current source reconstruction in MCG using a distributed current source model. We first test the efficiency of the inversion algorithm using a simulation model, selecting a short sequence of dipoles that generate dipolar magnetic fields. After adding noise to the calculated direct fields, the inverse computation is performed and the results are compared to the dipoles of the simulation data. The calculations are repeated with different levels of noise and different values of the regularization parameter, using only the normal components and all three components of the generated fields. The analysis of the magnetic field maps (MFM) sequence may help in identifying abnormalities during the ventricular repolarization. To assess the ability of the source reconstruction in detecting these disturbances, more complex simulation analyses can be performed, using a time series of dipoles that produces a sequence of MFMs as the ones generated by the normal heart activity. After introducing a perturbation in the activation of some dipoles in a specific region of the myocardium, inverse computation is performed to localize the heart activation inhomogeneities. The results show that 3D data allow finding a more accurate and stable solution.

• 2009-05-01

著者

• De Melis

  Graduate school of advanced science and technology, Tokyo Denki University

• De Melis

  Graduate School Of Advanced Sci. And Technol. Tokyo Denki Univ.

• De Melis

  Graduate School Of Advanced Science And Technology Tokyo Denki University

• TANAKA K.

  School of Science and Engineering, Tokyo Denki University

• UCHIKAWA Y.

  Graduate School of Advanced Science and Technology, Tokyo Denki University

関連論文

• Discussion of Source Reconstruction Models Using 3D MCG Data
• Single and Distributed Dipole Models Analysis of Cardiac Source Activation using MCG Signals
• Analysis of Standard and Irregular Patterns in a Simulated Human Magnetocardiogram
• Discussion of Current Distribution of Exercise 3D MCG Using an Inhomogeneous Human Volume Conductor
• Discussion of source reconstruction models using 3D MCG data (特集 バイオエレクトロニクスと生体情報工学)
• Analysis of 3-D Somatosensory Evoked Field with Dynamic Singular Value Decomposition

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