Spinal Epidural Granulocytic Sarcoma in a Child Precedent to Clinical Manifestation of Acute Myeloid Lymphoma : Case Report

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概要

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• A 13-year-old boy presented with an epidural thoracic granulocytic sarcoma manifesting as rapidly progressive paraplegia preceding clinical manifestation of acute myeloid leukemia (AML). Magnetic resonance imaging revealed a thoracic epidural tumor. He underwent emergent laminectomy and the tumor was totally resected. The initial histological diagnosis was malignant lymphoma. The correct diagnosis of epidural granulocytic sarcoma and AML was established based on cell-surface markers and a chromosomal study of the bone marrow cells. A combination of chemotherapy and bone marrow transfusion achieved complete remission of leukemia. No evidence of AML has emerged over the 18-month follow-up period. Granulocytic sarcoma should be considered in the differential diagnosis of an epidural mass in pediatric patients with or without acute leukemia. Immediate diagnosis and appropriate treatment are recommended to prevent leukemic transformation.

• 社団法人　日本脳神経外科学会の論文
• 2009-05-15

著者

• YAMAGUCHI SATOSHI

  Department of Surgery, Nagasaki Prefectural Shimabara Hospital

• Kurisu Kaoru

  Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University

• Kurisu K

  Department Of Neurosurgery Graduate School Of Biomedical Science Hiroshima University

• Kurisu Kaoru

  鹿児島大学 医歯学総合研究科脳神経外科学

• Kurisu Kaoru

  国立病院機構東広島医療センター

• Kurisu Kaoru

  西広島リハビリテーション病院 リハビリテーション科

• NISHIMURA Shinichiro

  Department of Pediatrics, Graduate School of Biomedical Sciences, Hiroshima University

• Nishimura Shinichiro

  Department Of Pediatrics Hiroshima University Graduate School Of Biomedical Sciences

• Nishimura Shinichiro

  Department Of Pediatrics Graduate School Of Biomedical Sciences Hiroshima University

• Kurisu Kaoru

  Department Of Neurosurgery Hiroshima University Graduate School Of Biomedical Sciences

• Kurisu Kaoru

  Department Of Neurosurgery

• EGUCHI Kuniki

  Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University

• KOBAYASHI Masao

  Department of Pediatrics, Hiroshima University Graduate School of Biomedical Sciences

• TAKEDA Masaaki

  Department of Neurosurgery, Hiroshima University Graduate School of Biomedical Sciences

• KAJIUME Teruyuki

  Department of Pediatrics, Hiroshima University Graduate School of Biomedical Sciences

• Kaoru Kurisu

  Department Of Neurosuegery Graduate School Of Biomedical Sciences Hiroshima University

• Eguchi Kuniki

  Department Of Neurosurgery Graduate School Of Biomedical Sciences Hiroshima University

• Eguchi Kuniki

  Department Of Neurosurgery Hiroshima University Graduate School Of Biomedical Sciences

• Takeda Masaaki

  Department Of Neurosurgery Hiroshima University Graduate School Of Biomedical Sciences

• Takeda Masaaki

  Department Of Electrical Engineering Nagoya University

• Kobayashi Masao

  Department Of Pediatrics Graduate School Of Biomedical Sciences Hiroshima University

• Yamaguchi Satoshi

  Department Of Applied Chemistry Graduate School Of Engineering Kyushu University

• Kobayashi Masao

  Department Of Pediatrics And Medicine Medical University Of South Carolina

• Yamaguchi Satoshi

  Department Of Agricultural Chemistry Faculty Of Agriculture Kyushu University

• Nishimura Shinichiro

  Department Of Diagnostic Radiology Graduate School Of Medical Sciences Kumamoto University

• Yamaguchi Satoshi

  Department Of Neurosurgery Hiroshima University Graduate School Of Biomedical Sciences

• Kajiume Teruyuki

  Department Of Pediatrics Hiroshima University Graduate School Of Biomedical Sciences

• YAMAGUCHI Satoshi

  Department of Neurosurgery, Hiroshima University Graduate School of Biomedical Sciences

• KOBAYASHI MASAO

  Department of Chemical Engineering, Faculty of Engineering Science, Osaka University

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