トリフルオロメチル基含有ピリジン類の合成と生理活性分子への応用
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概要
- 論文の詳細を見る
Heteroaromatic compounds are widely distributed in nature and often found in numerous biologically active natural products, agrochemicals, drugs, dyes, polymers, etc. because they usually have various chemical and physicochemical properties. In particular, pyridines are one of the most important heteroaromatic compounds and thus widely applied as biologically active compounds and organic materials. Trifluoromethyl-containing heteroaromatic compounds often have extremely unique properties and therefore have been studied during the last several decades. In fact, some of such compounds are currently widely utilized as commercialized agrochemicals, drugs etc. as well as drug candidates under development. This review introduces synthesis of several trifluoromethyl-containing pyridines and their applications to biologically active molecules.
- 社団法人 有機合成化学協会の論文
- 2009-10-01