Preliminary Research for Mutual Dose Perturbation Influence of ^<125>I Brachytherapy Source

概要

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For two arrangement modes of two 125I brachytheray sources, a homo-longitudinal axis and a homo-transverse axis, the sum of dose distributions caused by each single source and actual dose distribution of the two coexisting sources are calculated separately in a clinically interested area by Monte Carlo simulation. Comparisons between them are used to evaluate the mutual dose perturbation influence. The result shows, for the homo-longitudinal axis arrangement, obvious perturbation can be observed along the longitudinal direction when the distances between sources’ centers, L, are 0.5 cm and 1.0 cm, up to 11.7±0.4% and 4.8±0.2%, respectively, but, can be negligible for the distance exceeding 2.0 cm. For the homo-transverse axis arrangement, the range of dose perturbation depends on the source length and distances between sources’ centers, and an influence extent is greater than the former, e.g., 27.2±1.1%, 15.4±0.6%, and 7.0±0.3% maximum for L=0.5 cm, 1.0 cm, and 2.0 cm, respectively. As for dose perturbation induced by the source leaning which happened in actual implant sometimes, the result indicates a dose fluctuation became more acute with obliquity increasing. The maximum dose increasing, 54.5±2.1% and 199.7±7.8%, and the maximum dose decreasing, 42.6±1.7% and 64.9±2.6%, could be observed for 10° and 30° obliquity with L=1.0 cm for the two arrangement modes respectively.
一般社団法人日本原子力学会の論文
2007-08-25