DNA damage-independent and -dependent signaling pathways in UVC-induced apoptosis : A chronological study

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概要

• 論文の詳細を見る
• 2000-08-04

著者

• Watanabe M

  Laboratory Of Radiation Biology Research Reactor Institute Kyoto University

• MORI TOSHIO

  Radioisotope Center, Nara Medical University

• Mori T

  Ri Center Nara Medical Univ.

• WATANABE MASAMI

  Department of Urology, Okayama University Graduate School of Medicine and Dentistry

• MATSUDA Naoki

  Radioisotope Center., Nagasaki Univ.

• Matsuda Naoki

  Ctr. Frontier Life Sci. Nagasaki Univ.

• Okumura Yutaka

  Ctr. Frontier Life Sci. Nagasaki Univ.

• HORIKAWA Miwa

  Ctr. Frontier Life Sci. Nagasaki Univ.

• YOSHIDA Masahiro

  Ctr. Frontier Life Sci. Nagasaki Univ.

• YOSHIDA Masahiro

  Radioisotope Ctr. Nagasaki Univ.

• OKUMURA Yutaka

  Radioisotope Ctr. Nagasaki Univ.

• HORIKAWA Miwa

  Department of Radiation Life Sciences, School of Pharmaceutical Sciences, Nagasaki University

• Watanabe Masami

  Lab. Of Radiation Biology Div. Of Radiation Life Sci. Res. Reactor Inst. Kyoto Univ.

• Watanabe Masami

  Department Of Urology Okayama University Graduate School Of Medicine And Dentistry

• Watanabe Masami

  Department Of Perinatology Institute For Developmental Research

• Watanabe Masami

  Department Of Radiation Life Sciences School Of Pharmaceutical Sciences Nagasaki University

• Watanabe Masami

  Department of Applied Chemistry, Faculty of Science, Science University of Tokyo

関連論文

• Phosphorylated H2AX Foci in Tumor Cells Have No Correlation with Their Radiation Sensitivities
• Time Course and Spacial Distribution of UV Effects on Human Skin in Organ Culture
• Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors : its Independency of p53 Status
• 3-Amino-1, 4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) Sensitizes Mammalian Cells to UV Radiation by Causing The S-Phase Arrest, Not by Inhibiting The Repair of DNA Damage as Observed in Escherichia coli
• Three-Dimensional Analysis of Nuclear Localization of Repair Sites of UV-lnduced DNA Damage by Laser Scanning Confocal Microscopy in Human Cells
• Meldnin reduces ultraviolet-induced DNA damdge formation and killing rate in cultured human melanoma cells treated with DHA.
• The Relationship Between Residual Interphase Chromosome Breakage and Cellular Radiosensitivity in Transformed Syrian Golden Hamster Cells
• Effective Suppression of Bystander Effects by DMSO Treatment of Irradiated CHO Cells
• Absence of G1 arrest after X-ray irradiation in cancer cells with wild-type p53
• Biological effect of radiation-induced long life radicals
• Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells
• Introduction of a Normal Human Chromosome 8 Corrects Abnormal Phenotypes of Werner Syndrome Cells Immortalized by Expressing an hTERT Gene
• Delayed Induction of Telomere Instability in Normal Human Fibroblast Cells by Ionizing Radiation
• 226 Radiation-induced delayed chromosomal instability caused by large deletion(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 223 Radiation-Induced Delayed Chromosomal Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 221 A Role of DNA Double Strand Break Repair in the Induction of Genetic Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 214 The complementation of abnormal phenotypes of Werner syndrome cells by expressing WRN gene(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-2-3 Radiation-Induced Delayed Chromosome Aberrations(Radiation Induced Genetical Instability : What Is the Mechanism That a Cell Memorizes Being Irradiated?, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Instability of a Human Chromosome Exposed to Radiation in Unirradiated Mouse Cells
• The Role of DNA-PKcs Function on Induction of Genetic Instability by Radiation
• Radiation-induced genomic instability caused by large deletion (position)
• Phenotypic Reversion of an X-Ray-Induced Transformant of Mouse m5S by Introduction of a Human Chromosome 11
• The Effect of DNA Repair Defects on the Induction of Delayed Chromosome Aberrations by Radiation
• Involvement of Telonomic Instability in the Formation of Delayed Chromosome Aberrations Induced by Radiation
• Evidence for Induction of DNA Double Strand Breaks in the Bystander Response to Targeted Soft X-Rays in Repair Deficient CHO Cells
• Minimal invasiveness and effectivity of subinguinal microscopic varicocelectomy : a comparative study with retroperitoneal high and laparoscopic approaches
• Varicocele rupture due to sexual intercourse
• Increased Chromosome Instability and Accumulation of DNA Double-strand Breaks in Werner Syndrome Cells
• Biochemical Markers for in Situ Detection of DNA Double Strand Breaks in Cultured Mammalian Cells
• Exogenous Expression of Exonuclease Domain-deleted WRN Interferes with the Repair of Radiation-induced DNA Damages
• Differences in Effects of Oncogenes on Sensitivity to Anticancer Drugs
• Involvement of Reactive Oxygen Species (ROS) in the Induction of Genetic Instability by Radiation
• 225 Influence of Reactive Oxygen Species in the Induction of Genetic Instability by Radiation(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 222 X-ray-induced genomic instability in Atm knock-out mouse cells(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 220 Mechanism of radiation-induced delayed mutagenesis(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 217 Localization of Phosphorylated H2AX and Phosphorylated p53 in Cells Inducing X-ray-induced Senescence-like Growth Arrest(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 168 Mechanism of cell cycle-dependent cell death by heat shock(Radio-protection and sensitization, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 141 The role of site-specific phosphorylation on X-ray-induced p53 accumulation(Redox regulation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Inhibition of Pancreatic Carcinogenesis by Shark Cartilage Proteoglycan in Hamsters
• DNA Repair Effect of Traditional Sweet Pepper Fushimi-togarashi : Seen in Suppression of UV-induced Cyclobutane Pyrimidine Dimer in Human Fibroblast
• Radiation-Induced Chromosome Damage in G_1 Phase Cells as Breaks in Permature Chromosome Condensation (PCC) and Its Biological Meaning
• 104 DNA Damage-Induced Phosphorylation of Histone H2AX and Alteration of Chromatin Structure(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 97 A Role of WRN Protein in the Recovery from DNA Replication Arrest(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Induction of Micronuclei in CHO Cells by Bleomycin but not by X-irradiation is Decreased by Treatment with HMG-CoA Reductase Inhibitors
• Involvement of reactive oxygen species (ROS) in the induction of genetic instability by radiation
• Characterization of X-ray-induced Mutation in Werner Syndrome Cells
• Effect of introduction of a normal chromosome 8 on Werner syndrome cells
• Phosphorylated ATM Foci as a Biochemical Marker for DNA Double Strand Breaks
• Mechanism of radiation-induced delayed mutagenesis
• Delayed Induction of DNA Damage and Activation of p53 in X-ray Surviving Cells
• Participation of ATM function in X-ray-induced delayed chromosomal instability
• Biological Action of Curcumin on Transformed Mouse Cells
• Biological Action of Curcumin on Transformed Mouse Cells
• Role of Ser15, Thr18, and Ser20 phosphorylation in p53 stabilization after X-irradiation
• Suppressive Effect of p53 on Heat-induced Multiple Centrosomes
• In vitro transformation system using hTERT-transfected normal human diploid cells
• An Alternative Mechanism for Radioprotection by Dimethyl Sulfoxide; Possible Facilitation of DNA Double-strand Break Repair
• INTER-LABORATORY VALIDATION STUDY OF THE SKIN^2 DERMAL MODEL ZK1100 AND MTT CYTOTOXICITY ASSAY KITS
• INTERLABORATORY VALIDATION STUDY OF THE SKIN^2 DERMAL MODEL AND MTT CYTOTOXICITY ASSAY KITS
• Mode of Gene Damage Induced by Exposure to UVB and Some Radical Species (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
• Radiation-induced delayed damage in scid mouse cells
• 118 Responses of cultured cells to chronic low-dose rate UV-B irradiation(Effects of UV & sunlight, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• UVB/UVC-responsive Intracellular Signaling Pathways : A Chronological and Comparative Study.
• DNA damage-independent and -dependent signaling pathways in UVC-induced apoptosis : A chronological study
• Mechanism of p53 Accumulation and Activation by Ionizing Radiation and Telomere Shortening
• Phosphorylation of p53 caused by radiation and telomere-shortening
• Extensive biopsy using a combined transperineal and transrectal approach to improve prostate cancer detection
• Magnetohydrodynamic and Tearing Instabilities in a Tokamak
• In Situ Visualization of UV-Induced DNA Damage in Human Cell Nuclei Following Partial-Volume Irradiation.
• In Situ Visualization of UV-Induced DNA Damage and Its Repair in Human Fibroblasts
• Effect of Nonenzymatic Glycosylation on the Titers of Circulating Autoantibodies in Pemphigus and Pemphigoid
• Three-Dimensional Visualization of UV-Induced DNA Damage and Its Repair in Human Cells.
• 211 Effect of RibCys on scavenging long-lived radicals and reducing gene mutation in mammalian cells by adding AFTER irradiation(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Trp-P-1 inhibits the removal of both cyclobutane dimers and (6-4)photoproducts from the DNA of ultraviolet-inadiated E.coli.
• Molecular analysis of p53 protein expression through signal transduction pathway in normal human cells following X-irradiation.
• Inhibitory Effect of Curcumin on the Growth of Transformed Mouse Cells
• Regulatory mechanisms of MAP kinase activation in response to UVC irradiation.
• Mechanism of Interaction of c-Abl with ATM Protein and DNA-PK.
• Involvement of Long-Lived Radicals Induced by Radiation in the Induction of Mutation
• Suppression of Radiation-Induced Mutation by an Anti-Oxidant Material
• Repression of DNA synthesis in UV-inadiated xeroderma pigmentosum variant cells is more severe than normal cells
• Induction of Gene Mutation and Cancer by Extra-DNA Bystander Effect of Long-lived Protein Radicals inGamma Ray Irradiated Mammalian Cells.
• Scavenging of long-lived radicals by (?)-epigallocatechin-3-O-gallate and simultaneous suppression of mutationin irradiated mammalian cells
• Proteolytic fragmentation and sugar chains of plasma ADAMTS13 purified by a conformation-dependent monoclonal antibody
• Free radicals with long lifetime in γ-irradiated GHE cells and their model system at 295 K. Decay kinetics and reaction with vitamin C.
• Safety Evaluation and Toxicity Testing Using In Vitro Methods
• S-6-2 Long-Lived Radicals (LLR) Causes Genotoxic Effects(Biological Effects of Long-lived Radicals Induced by Radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Apoptotic death of beta cells induced by optic nerve transection in adult cat retinas
• Mechanism of delayed mutagenesis by radiation-induced genomic instability
• Enhanced Cell Proliferation by X-Irradiated Conditioned Medium
• Expression of p53 and p21 proteins after ionizing irradiation in tumor cells express wild-type p53
• Accumulation and activation of p53 protein through its phosphorylation and acetylation after heat shock
• Dose-dependent bi-phasic accumulation of p53 protein in normal human embryo cells following X-irradiation
• Effect of low dose of X-rays on chromosome constitution in human embryo cells during long term culture
• Role of Gadd45 gene in X-ray-induced G_1 arrest in human cells
• 219 Establishment and characterization of monoclonal antibodies against 2-acetylaminofluorene-DNA adducts(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• The Amount of DNA Damage Determines Ultraviolet-Radiation-Induced Cytotoxicity after Uniform- or Local-Cell Irradiation
• In Situ Visualization of UV-Microbeam-Induced DNA Damage Repair in Human Fibroblasts
• Radiation-Induced Genetic Instability in Scid Mouse Cells
• Radiation-Induced Delayed Chromosome Instability Studied by a Microcell-Mediated Chromosome Transfer

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