Magnetic Resonance Spectra of Hyperpolarized ^<129>Xe in Human Blood and Living Rat Chest
スポンサーリンク
概要
- 論文の詳細を見る
We constructed a gas polarization system to test the feasibility of using hyperpolarized 129Xe gas as an NMR (nuclear magnetic resonance) probe to explore brain function. Both in vitro and in vivo experiments were performed with a 4.7T NMR spectrometer. Xenon spectra from human blood confirmed the existence of two peaks corresponding to red blood cells and plasma. In rat studies, three peaks at around 200 ppm were observed. Our results are consistent with previously reported data.
- 日本磁気共鳴医学会の論文
- 2003-12-31
著者
-
Ito H
National Inst. Radiological Sci. Chiba Jpn
-
Kershaw Jeff
Akita Research Institute Of Brain And Blood Vessels
-
Kanno Iwao
秋田県立脳血管研究センター
-
Kanno I
Department Of Radiology And Nuclear Medicine Akita Research Institute Of Brain And Blood Vessels
-
Iida Hidehiro
Department Of Investigative Radiology National Cardiovascular Center Research Institute
-
Ito Hiroshi
Molecular Neuroimaging Group Molecular Imaging Center National Institute Of Radiological Sciences
-
Kanno Iwao
Akita Research Institute Of Brain And Blood Vessels
-
Iida H
Department Of Investigative Radiology Research Institute National Cardio Vascular Center
-
Iida Hidehiro
Department Of Internal Medicine Radiology
-
Tamura Hajime
Faculty Of Medicine Tohoku University
-
WAKAI Atsushi
Akita Research Institute of Brain and Blood Vessels
-
NAKAMURA Kazuhiro
Akita Research Institute of Brain and Blood Vessels
-
KONDOH Yasushi
Akita Research Institute of Brain and Blood Vessels
-
Kanno Iwao
Department Of Radiology And Nuclear Medicine Akita Research Institute For Brain And Vessels
-
Iida Hidehiro
Department Of Investigative Radiology Research Institute National Cardio Vascular Center
-
Tamura Hajime
Faculty Of Engineering Utsunomiya University
-
Nakamura Kazuhiro
Akita Industry Promotion Foundation
-
Iida Hidehiro
Department Of Gastroenterological Surgery Osaka University Graduate School Of Medicine
-
Iida Hidehiro
Department Of Bio-medical Imaging National Cerebral And Cardiovascular Center Research Institute
関連論文
- Use of a compact pixellated gamma camera for small animal pinhole SPECT imaging
- ＜Poster＞Cerebrovascular dynamics in response to neural stimulation
- Effects of image reconstruction algorithm on neurotransmission PET studies in humans : comparison between filtered backprojection and ordered subsets expectation maximization
- Combined Autologous Cellular Cardiomyoplasty Using Skeletal Myoblasts and Bone Marrow Cells for Human Ischemic Cardiomyopathy with Left Ventricular Assist System Implantation : Report of a Case
- Development of motion correction technique for cardiac ^O-water PET study using an optical motion tracking system
- Influence of residual oxygen-15-labeled carbon monoxide radioactivity on cerebral blood flow and oxygen extraction fraction in a dual-tracer autoradiographic method
- Optimal scan time of oxygen-15-labeled gas inhalation autoradiographic method for measurement of cerebral oxygen extraction fraction and cerebral oxygen metabolic rate
- Accelerated 3D-OSEM image reconstruction using a Beowulf PC cluster for pinhole SPECT
- System design and development of a pinhole SPECT system for quantitative functional imaging of small animals
- Understanding of cerebral energy metabolism by dynamic living brain slice imaging system with [^F]FDG
- Development of a Hyperpolarized ^Xe System on 3T for the Rat Lungs
- Dependency of energy and spatial distributions of photons on edge of object in brain SPECT
- Evaluation of a commercial PET tomograph-based system for the quantitative assessment of rCBF, rOEF and rCMRO_2 by using sequential administration of ^O-labeled compounds
- Successful treatment of primary central nervous system lymphoma in an elderly patient
- Arterial fraction of cerebral blood volume in humans measured by positron emission tomography
- Effects of scatter correction on regional distribution of cerebral blood flow using I-123-IMP and SPECT
- Regional cerebral blood flow, blood volume, oxygen extraction fraction, and oxygen utilization rate in normal volunteers measured by the autoradiographic technique and the single breath inhalation method
- Myocardial FDG-PET examination during fasting and glucose loading states by means of a one-day protocol
- Copper-62 ATSM as a hypoxic tissue tracer in myocardial ischemia
- Brain perfusion SPECT study with ^ Tc-bicisate : Clinical pitfalls and improved diagnostic accuracy with a combination of linearization and scatter-attenuation correction
- Acute effects of stereotactic radiosurgery on the kinetics of glucose metabolism in metastatic brain tumors : FDG PET study
- Evaluation of ^Cu labeled diacetyl-bis(N^4-methylthiosemicarbazone) as a hypoxic tissue tracer in patients with lung cancer
- Usefulness of ECG gated N-13 ammonia positron emission tomography for assessing global and regional left ventricular function
- Quantitative assessment of truncal FDG-PET examination with postinjection transmission scan : Comparison with preinjection transmission scan
- REGIONAL LUNG FUNCTION IN PULMONARY HYPERTENSION : Original Articles written in English
- ^C-Methionine Uptake to the Pancreas and Its Secretion : A Positron Emission Tomography Study in Humans
- Use of automated image registration to generate mean brain SPECT image of Alzheimer's patients
- Regional cerebral blood flow abnormalities in late-life depression : Relation to refractoriness and chronification
- Recovery of Learning and Memory by Gene Therapy Using Hepatocyte Growth Factor Gene After Focal Cerebral Ishcemia in Rats(Gene Therapy/Genetic Engineering (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Evaluation of utility of asymmetric index for count-based oxygen extraction fraction on dual-tracer autoradiographic method for chronic unilateral brain infarction
- ＜Poster＞Neurovascular coupling studies in awake-behaving mice
- Three-dimensional SPECT reconstruction with transmission-dependent scatter correction
- Quantitative analysis of dopamine transporters in human brain using [^C]PE2I and positron emission tomography : evaluation of reference tissue models
- A comparison of Tc-99m HMPAO brain SPECT images of young and aged normal individuals
- A method for the quantification of benzodiazepine receptors by using ^I-iomazenil and SPECT with one scan and one blood sampling
- Error analysis of autoradiography method for measurement of cerebral blood flow by ^I-IMP brain SPECT: A comparison study with table look-up method and microsphere model method
- Error analysis of table look-up method for cerebral blood flow measurement by ^I-IMP brain SPECT: Comparison with conventional microsphere model method
- Pulmonary Function in Pulmonary Hypertensive State with Special Reference to Regional Distribution of Ventilation and Perfusion
- PULMONARY CIRCULATION IN RELATION WITH VENTILATION USING COMPUTER ASSISTED SCINTILLATION CAMERA : PROCEEDINGS OF THE 37TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Magnetic Resonance Spectra of Hyperpolarized ^Xe in Human Blood and Living Rat Chest
- Hemodynamic changes during neural deactivation in human brain : A positron emission tomography study of crossed carebellar diaschisis
- Performance of list mode data acquisition with ECAT EXACT HR and ECAT EXACT HR+ positron emission scanners
- OJ-094 Delayed Post-ischemic Treatment with Fluvastatin Improved Learning and Memory Deficit After Stroke in Rats without affecting Infarction Volume(Cerebrovascular circulation / Stroke-1, The 71st Annual Scientific Meeting of the Japanese Circulation So
- PJ-654 Post-ischemic Administration of Fluvastatin Improves Cognitive Dysfunction in the Chronic Stage of Cerebral Infarction in Rat Model(Cerebrovascular circulation/Stroke-3 (H) PJ110,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meet
- PJ-652 Over-expression of HGF Improves Learning and Memory and Prevents Progressive Shrinkage of Thalamus in the Chronic Stage of Cerebral Infarction(Cerebrovascular circulation/Stroke-3 (H) PJ110,Poster Session (Japanese),The 70th Anniversary Annual Scie
- Evaluation of Arteriolar Hyalinosis of the Skin of Patients With Chronic Congestive Heart Failure
- Therapeutic Efficacy of Basic Fibroblast Growth Factor on Experimental Focal Ischemia Studied by Magnetic Resonance Imaging
- A Method for Measuring the Decay Time of Hyperpolarized ^Xe Magnetization in Rat Brain without Estimation of RF Flip Angles
- Changes in human cerebral blood flow and myocardial blood flow during mental stress measured by dual positron emission tomography
- Mapping of central dopamine synthesis in man, using positron emission tomography with L-[β-^C]DOPA
- Increased arteriolar hyalinosis and thioredoxin expression of skin in patients with chronic heart failure
- Brain and whole body distribution of N-isopropyl-4-iodoamphetamine (I-123) in humans : Comparison of radiopharmaceuticals marketed by different companies in Japan
- Database of normal human cerebral blood flow measured by SPECT : II. Quantification of I-123-IMP studies with ARG method and effects of partial volume correction
- Database of normal human cerebral blood flow measured by SPECT : I. Comparison between I-123-IMP, Tc-99m-HMPAO, and Tc-99m-ECD as referred with O-15 labeled water PET and voxel-based morphometry
- Apparent CBF decrease with normal aging due to partial volume effects : MR-based partial volume correction on CBF SPECT
- Effects of tissue heterogeneity on cerebral vascular response to acetazolamide stress measured by an I-123-IMP autoradiographic method with single-photon emission computed tomography
- Error analysis of measured cerebral vascular response to acetazolamide stress by I-123-IMP autoradiographic method with single photon emission computed tomography : Errors due to distribution volume of I-123-IMP
- Regional differences in distribution volume of I-123 IMP in the human brain : Effect on CBF calculated by ARG method
- Improvement of likelihood estimation in Logan graphical analysis using maximum a posteriori for neuroreceptor PET imaging
- No inhibitory effect on P-glycoprotein function at blood-brain barrier by clinical dose of clarithromycin : a human PET study with [^C]verapamil
- Measurement of cerebral blood flow by the autoradiographic method with N-isopropyl-4-[I-123] iodoamphetamine : comparison of radiopharmaceuticals marketed by different companies in Japan
- N-isopropyl-4-[^I]iodoamphetamine (^I-IMP) products : a difference in radiochemical purity, unmetabolized fraction, and octanol extraction fraction in arterial blood and regional brain uptake in rats
- Effects of smoking on the lung accumulation of [^C]McN5652
- Recurrent thymoma : radiological (CT and FDG-PET) and histological (WHO criteria) features
- Human cerebral circulation : positron emission tomography studies
- Scatter and cross-talk correction for one-day acquisition of ^I-BMIPP and ^Tc-tetrofosmin myocardial SPECT
- Usefulness of asialoglycoprotein receptor imaging for the evaluation of liver metastasis of neuroblastoma
- Long-Term Prognostic Value of Normal Adenosine Triphosphate-Stress Thallium-201 Myocardial Perfusion Imaging and Usefullness of Washout Rate Analysis for Risk Stratification
- Effect of Regional Tracer Delay on CBF in Healthy Subjects Measured with Dynamic Susceptibility Contrast-Enhanced MRI : Comparison with ^O-PET
- PET measurements of CBF, OEF, and CMRO_2 without arterial sampling in hyperacute ischemic stroke : Method and error analysis
- Estimation of Absorbed Dese Using Activity Measured by PET for Continuous Inhalation of C^O_2 and ^O_2
- -0392- RELATIONSHIP BETWEEN ABSOLUTE MYOCARDIAL BLOOD FLOW, OXYGEN METABOLISM BY POSITRON EMISSION TOMOGRAPHY(PET) WITH O-15 WATER AND 201-THALLIUM(TL), 123-I-BMIPP(BM)SPECT IN THE PATIENTS WITH OLD MYOCARDIAL INFARCTION(OMI)(PROCEEDINGS OF THE 59th ANNUA
- Stimulus frequency dependence of the linear relationship between local cerebral blood flow and field potential evoked by activation of rat somatosensory cortex
- THE FREQUENCY DEPENDENT OF RELATIONSHIP BETWEEN LCBF AND FIELD POTENTIALS BY HIND PAW STIMULATION IN RAT(Physiology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
- Improvement of the Relative Permittivity Evaluation with a Whispering-Gallery Mode Dielectric Resonator Method(Special Issue on Microwave and Millimeter Wave Technology)
- Carbon Monoxide Poisoning : Two Cases of Assessment by Magnetization Transfer Ratios and ^1H-MRS for Brain Damage
- Sacral insufficiency fracture detected by FDG-PET/CT : Report of 2 cases
- Evoked local cerebral blood flow induced by somatosensory stimulation is proportional to the baseline flow
- Modulation of Evoked Cerebral Blood Flow under Excessive Blood Supply and Hyperoxic Conditions
- Regional Brain Activitiy during Face and Word Discrimination--Simultaneous Recording of Event-related Potentials and Positron Emission Tomography
- CBF Change Evoked by Somatosensory Activation Measured by Laser-Doppler Flowmetry: Independent Evaluation of RBC Velocity and RBC Concentration
- Cerebral perfusion changes in traumatic diffuse brain injury; IMP SPECT studies
- Development of porcine model for old myocardial infarction and assessment system for therapeutic trials of myocardial regeneration medicine using positron emission tomography (PET)
- Positron emission tomography inter-scanner differences in dopamine D_2 receptor binding measured with [^C]FLB457
- Optimization of transmission scan duration for ^O PET study with sequential dual tracer administration using N-index
- Contribution of nitric oxide to cerebral blood flow regulation under hypoxia in rats
- Effect of cyclooxygenase-2 on the regulation of cerebral blood flow during neuronal activation in the rat
- Parametric imaging in nuclear medicine
- Is state-dependent alternation of slow dynamics in central single neurons during sleep present in the rat ventroposterior thalamic nucleus?
- Monte Carlo simulation of scintillation photons for the design of a high-resolution SPECT detector dedicated to human brain
- Three-dimensional brain phantom containing bone and grey matter structures with a realistic head contour