維持透析患者における腹部大動脈石灰化係数および脈波速度に関する検討

概要

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We investigated the relationship among the abdominal aortic calcification index (ACI), pulse wave velocity (PWV), and several clinical and biochemical parameters in chronic hemodialysis patients. ACI and PWV were measured in 122 dialysis patients (79 men, 43 women) with a mean age (±SD) of 57.8±13.6 years. ACI was calculated with computed tomographic scanning of the abdomen. Brachial-ankle PWV and blood chemistry data were obtained before hemodialysis treatment. There was a significantly positive correlation between ACI and PWV (r=0.466, p<0.001). ACI and PWV were each highly correlated with patient age (ACI: r=0.428, p<0.001, PWV: r=0.610, p<0.0001). ACI was significantly higher in diabetic patients than in non-diabetic patients (30.2±19.5 versus 21.0±23.4%, p<0.05). PWV was correlated with systolic blood pressure (r=0.397, p<0.001). ACI, which is morphological assessment for atherosclerosis was statistically correlated with PWV, which is a functional test for atherosclerosis. In this study, age, diabetes, and systolic blood pressure were found to be the contributing factors to atherosclerosis.
社団法人日本透析医学会の論文
2003-09-28