クローン病肛門病変の経過 : 痔瘻・膿瘍症例と腸管病変との関連を中心に

概要

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A perianal abscess/fistula in Crohn's disease gives the patients severe pain and discomfort, and negatively affects the quality of life. We examined the clinical course of perianal abscess/fistula, and studied how to relate to intestinal disease in Crohn's disease.<BR>One hundred two patients with perianal abscess/fistula were treated for intesinal disease of Crohn's disease in our institute for the past 12 years. Follow-up was undertaken at a minimum of 12 to 142 months (mean 70.6). The clinical course of perianal abscess/fistula was judged by our criteria based on subjective symptoms. In each patient, intesinal disease was evaluated by radiographic findings near the time of examination of the perianal region.<BR>Seventy-one out of 102 patients (69.6%) had satisfactory progress during the follow-up periods. There was no relation between the occurrence of perianal abscess/fistula and intestinal disease, but the exacerbation of perianal abscess/fistula was connected with involving the large intestine, particularly the rectum.<BR>In treatment for perianal abscess/fistula in Crohn's disease, it is necessary to control serious lesions of the rectum, avoiding to spoil the rectal sphincter function.