Underdevelopment of Fetal Thyroid Follicular Cells in Athymic Nude Mouse (BALB/cAnNCrj-nu/nu) Observed by Electron Microscopic Morphometry
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概要
- 論文の詳細を見る
Fetal thyroid follicular cells of congenitally athymic nude mouse (BALB/cAnNCrj-nu/nu) were studied with an electron microscope. The area of the entire cell, nucleus and mitochondrion were measured and compared in athymic and euthymic fetal nude mice (BALB/cAnNCrj-nu/+) at 18 days of gestation. The mean area of cytoplasm was significantly smaller in homozygous athymic nude mice than in heterozygous euthymic ones. The mean area of the mitochondrion was also smaller in homozygous athymic nude mice, but the difference was not statistically significant. There was no significant difference between the two groups in the area of the nucleus. These findings suggest that the thyroid gland of athymic nude mice is still underdeveloped at the end of gestation as compared to that of their euthymic littermates.
- 社団法人 日本実験動物学会の論文
著者
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INOMATA Tomo
Department of Laboratory Animal Science, School of Veterinary Medicine, Azabu University
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NINOMIYA Hiroyoshi
Department of Laboratory Animal Science, School of Veterinary Medicine, Azabu University
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Inomata Tomo
Laboratory Of Experimental Animal Science Graduate School Of Veterinary Science Azabu University
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Inomata Tomo
Department Of Laboratory Animal Science School Of Veterinary Medicine Azabu University
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SAKITA Katsuyasu
Department of Laboratory Animal Science, Azabu University
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Ninomiya Hiroyoshi
Department Of Laboratory Animal School Of Veterinary Medicine Azabu University
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SAKITA Katsuyasu
Japan Pet Care Association
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HOSHI Satoko
Department of Laboratory Animal Science, Azabu University
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Hoshi S
Okayama Univ. Okayama Jpn
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