Nutrirtonal Functions of Dietary Diacylglycerols

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We have investigated the nutritional and metabolic functions of dietary diacylglycerol and found that it has various beneficial effects for the human health when used as edible oils. We manufactured diacylglycerol-rich oil (DAG) containing more than 80wt% of diacylglycerol by using the immobilized-lipase. We also prepared a control triacylglycerol oil (TAG) which has the comparable fatty acid composition with DAG. The metabolic characteristics of DAG compared with TAG are likely to be based upon its chemical structure since the energy values and absorption coefficients of both oils are similar.The results of clinical studies using DAG are as follows:1. DAG lowered the magnitude of postprandial increase in serum and chylomicron triacylglycerol (TG) levels as compared with TAG in the single adminisitration study in humans.2. DAG prevented body fat accumulation, especially in visceral fat as measured by CT scan, in double-blind controlled study (DAG and TAG proup of 19 subjects each, 16 wks).3. The serum profiles (high density lipoprotein (HDL), TG and plasminogen activator inhibitor type-1) and anthropometric parameters (weight, body mass index, waist circumference and thickness of subcutaneous fat) were obviously improved by consuming DAG designed as cooking oil in free-living subjects (114 subjects, 1 yr). From these findings, DAG was considered to be effective in preventing obesity and to possibly prevent the life-style related diseases only by consuming as a daily cooking oil.
日本油化学会の論文
2001-05-01

Nutrirtonal Functions of Dietary Diacylglycerols

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