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Institute of Immunologiacal Science, Hokkaido University | 論文
- Tolerance to the anti-metastatic effect of lipopolysaccharide against liver metastasis in mice.
- Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R)-and 20(S)-Ginsenoside-Rg3, of Red Ginseng.
- A novel synthetic lipid A analog with low endotoxicity, DT-5461, prevents lethal endotoxemia.
- Inhibition of tumor-induced angiogenesis by a synthetic lipid Aanalogue with low endotoxicity, DT-5461.
- Vaccination of tumor cells transfected with B7-1 (CD80) gene Induces the'anti-metastatic effect and tumor immunity in mice.
- Functional role of sialyl lewis X and fibronectin-derived RGDS peptide analogue on tumor cell arrest in lungs followed by extravasation.
- Synthesis and biological properties of partially modified retro and retro-inverso pseudo peptides of Arg-Gly-Asp(RGD).
- Inhibition of tumor invasion and metastasis by peptidic mimetics of Arg-Gly-Asp(RGD) derived from the cell recognition site of fibronectin.
- Antimetastatic activities of synthetic Arg-Gly-Asp-Ser (RGDS) and Arg-Leu-Asp-Ser (RLDS) peptide analoguesand their inhibitory mechanisms.
- Apoptosis in human leukemic cells induced by lactoferricin, a bovinemilk protein-derived peptide:involvement of reactive oxygen species.
- Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin,inhibit tumor metastasis in mice.
- Effective synthesis of four isomeric trehalose dicorynomycolates(TDCMs) and their immunoadjuvant activities.
- Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN.
- Protective effect of mucosal administration of recombinant human macrophage colony-stimulating factor (rhM-CSF) on mucosal infection of Sendai virus in mice.
- Effect of MDP-Lys(L18) as a mucosal immunoadjuvant on protection of mucosal infections by Sendai virus and rotavirus.
- Characterization of the nucleocapsid protein of Hantaan virus strain 76-118 using monoclonal antibodies.
- Endotoxin antagonism by a synthetic lipid A analogue, T-5461, with low endotoxicity in human peripheral blood monocytes.
- Effect of MDP-Lys(L18), a derivative of MDP, on enhancing host resistance against Hantaan virus infection in newborn mice.
- Combination of anti-cell adhesive synthetic Arg-Gly-Asp-Ser analogue and anticancer drug doxorubicin heightens their original antimetastatic activites.
- Romurtide, a synthetic muramyl dipeptide derivative, promotes megakaryocytopoiesis through stimulation of cytokine production in nonhuman primates with myelosuppression.
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