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Fermentation and Biotechnology Laboratories, Astellas Pharma Inc. | 論文

• Scale-up fermentation of echinocandin type antibiotic FR901379(BIOCHEMICAL ENGINEERING)
• Improvement of FR901379 production by mutant selection and medium optimization(BIOCHEMICAL ENGINEERING)
• Purification and Molecular Characterization of a Quinoprotein Alcohol Dehydrogenase from Pseudogluconobacter saccharoketogenes IFO 14464
• Metabolic Engineering Study on the Direct Fermentation of 2-Keto-_L-Gulonic Acid, a Key Intermediate of _L-Ascorbic Acid in Pseudomonas putida IFO3738
• Cloning of a Gene for D-Sorbitol Dehydrogenase from Gluconobacter oxydans G624 and Expression of the Gene in Pseudomonas putida IFO3738
• FR198248, a New Anti-influenza Agent isolated from Aspergillus terreus No.13830 : I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities
• FR191512 , a Novel Anti-influenza Agent Isolated from a Fungus Strain No.17415 : II. Biological Properties
• FR191512 , a Novel Anti-influenza Agent Isolated from a Fungus Strain No.17415 : I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Structure Elucidation
• Strain selection and scale-up fermentation for FR901379 acylase production by Streptomyces sp. no. 6907(METHOD)
• Cloning and expression of the FR901379 acylase gene from Streptomyces sd. no. 6907
• Enhanced oxidative activities of cytochrome P450Rhf from Rhodococcus sp. expressed using the hyper-inducible expression system(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)

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