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北海道大学 薬研究 | 論文
- Recognition of Nucleotide Analogs Containing the 7,8-Dihydro-8-oxo Structure by the Human MTH1 Protein
- Formation of 5-Formy-dC from 5-Methyl-dC by γ-Irradiarion and FentonType Reactions
- New NTP analogs: the synthesis of 4'-thioUTP and 4'-thioCTP and their utility for SELEX
- PK-PD modeling of 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine and the enhanced antitumor effect of its phospholipid derivatives in long-circulating liposomes
- RNA interference induced by siRNAs modified with 4'-thioribonucleosides in cultured mammalian cells
- Mutagenicity of 5-Formylcytosine, an Oxidation Product of 5-Methylcytosine, in DNA in Mammalian Cells
- Synthesis and characterization of 2'-modified-4'-thioRNA: a comprehensive comparison of nuclease stability
- Synthesis and physical and physiological properties of 4'-thioRNA: application to post-modification of RNA aptamer toward NF-κB
- Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxycytidine: in vitro DNA polymerase reactions on DNA templates containing 5-formyl-2'-deoxycytidine
- Intracellular stability of 2'-OMe-4'-thioribonucleoside modified siRNA leads to long-term RNAi effect